The Poché Lab is seeking a highly motivated postdoctoral research associate/fellow with experience or interest in retinal developmental biology, tissue regeneration, or transcriptome analysis. This NIH R01-funded position is focused on the study of the molecular mechanisms blocking mammalian Müller glial cell (MG)-mediated retinal regeneration. Our long-term goal is to determine whether the mouse retina retains latent regenerative potential, akin to other vertebrate species, and whether we can genetically “awaken” that potential to restore sight.

Special emphasis will be placed on the investigation of MG transcriptional reprogramming to a progenitor-like state. Preference will be given to candidates with a strong background in mouse genetics and in techniques to probe the transcriptome and epigenome. This expertise should ideally include next gen sequencing (RNA-seq, ChIP-seq, ATAC-seq, single cell-seq, etc.) data analysis. However, training in these techniques can also be provided.

The Poché lab employs a multi-disciplinary approach utilizing genetic loss- and gain-of-function experiments, fate mapping, gene therapy, molecular biology, and live retinal confocal microscopy. In addition to technical training, all postdocs within the lab routinely receive one-on-one instruction in grant writing and presentation skills.

We are housed in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine (BCM). Located in the Texas Medical Center, the largest medical center on the world, BCM postdocs have a tremendous amount of technical and intellectual resources at their disposal, including the 26 BCM Advanced Technology Core Labs https://www.bcm.edu/research/research-services/atc-core-labs.

In your application, please include a cover letter, current CV, and contact information for three references. Application review will begin immediately and will continue until the position is filled. Please contact Dr. Poché at poche@bcm.edu.

The Poché Lab is seeking a highly motivated postdoctoral research associate/fellow with experience in mouse developmental genetics and embryology. This NIH R01-funded position is focused on studying the interplay between nutritional factors, such as vitamins, and genetic and metabolic pathways essential for embryonic development. Special emphasis will be given to neural crest-derived tissues. Our long-term goal is to use this information to devise new therapeutic strategies to modulate the development of neurocristopathies.

Preference will be given to candidates with a strong background in using genetic approaches to study either neural crest or cardiovascular development. This expertise should ideally include next gen sequencing (RNA-seq, ChIP-seq, ATAC-seq, single cell-seq, etc.) data analysis. However, training in these techniques can also be provided.

The Poché lab employs a multi-disciplinary approach utilizing genetic loss- and gain-of-function experiments, fate mapping, gene therapy, molecular biology, and live microscopy. In addition to technical training, all postdocs within the lab routinely receive one-on-one instruction in grant writing and presentation skills.

We are housed in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine (BCM). Located in the Texas Medical Center, the largest medical center on the world, BCM postdocs have a tremendous amount of technical and intellectual resources at their disposal, including the 26 BCM Advanced Technology Core Labs https://www.bcm.edu/research/research-services/atc-core-labs.

In your application, please include a cover letter, current CV, and contact information for three references. Application review will begin immediately and will continue until the position is filled. Please contact Dr. Poché at poche@bcm.edu.