Xuefei Tong, M.S.

I have over two decades of experience in using the mouse model and molecular biology to study fundamental aspects of development and disease.

Publications

  1. New genetic tools to define the pathophysiology of inborn errors of cobalamin metabolism impacting mammalian development. Chern T*, Tong X*, Bauer WG, Quispe-Parra DJ, Gao X, Gerner-Mauro KN, Poché RA. Differentiation. 2025 May 19;143:100868. doi: 10.1016/j.diff.2025.100868. Online ahead of print.PMID: 40411980. *Equal contribution.

  2. Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poché RA. Nat Commun. 2022 Jan 10;13(1):134. doi: 10.1038/s41467-021-27759-7.PMID: 35013307 

  3. Mouse models to study the pathophysiology of combined methylmalonic acidemia and homocystinuria, cblC type. Chern T, Achilleos A, Tong X, Hsu CW, Wong L, Poché RA. Dev Biol. 2020 Dec 1;468(1-2):1-13. doi: 10.1016/j.ydbio.2020.09.005. Epub 2020 Sep 14.PMID: 32941884 

  4. The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming. Rueda EM, Hall BM, Hill MC, Swinton PG, Tong X, Martin JF, Poché RA. Cell Rep. 2019 May 7;27(6):1637-1649.e6. doi: 10.1016/j.celrep.2019.04.047.PMID: 31067451

  5. The mito::mKate2 mouse: A far-red fluorescent reporter mouse line for tracking mitochondrial dynamics in vivo. Barrasso AP, Tong X, Poché RA. Genesis. 2018 Feb;56(2):10.1002/dvg.23087. doi: 10.1002/dvg.23087. Epub 2017 Dec 27.PMID: 29243279 

  6. Live imaging of developing mouse retinal slices. Barrasso AP, Wang S, Tong X, Christiansen AE, Larina IV, Poché RA.Neural Dev. 2018 Sep 15;13(1):23. doi: 10.1186/s13064-018-0120-y.PMID: 30219109 

  7. RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina. Poché RA, Zhang M, Rueda EM, Tong X, McElwee ML, Wong L, Hsu CW, Dejosez M, Burns AR, Fox DA, Martin JF, Zwaka TP, Dickinson ME. Cell Rep. 2016 Feb 23;14(7):1684-1697. doi: 10.1016/j.celrep.2016.01.039. Epub 2016 Feb 11.PMID: 26876175 

  8.  HNF1B Loss Exacerbates the Development of Chromophobe Renal Cell Carcinomas. Sun M, Tong P, Kong W, Dong B, Huang Y, Park IY, Zhou L, Liu XD, Ding Z, Zhang X, Bai S, German P, Powell R, Wang Q, Tong X, Tannir NM, Matin SF, Rathmell WK, Fuller GN, McCutcheon IE, Walker CL, Wang J, Jonasch E. Cancer Res. 2017 Oct 1;77(19):5313-5326. doi: 10.1158/0008-5472.CAN-17-0986. Epub 2017 Aug 14.PMID: 28807937